A practical method for n-methylation of indoles using dimethyl carbonate

X Jiang, A Tiwari, M Thompson, Z Chen…

Index: Jiang, Xinglong; Tiwari, Ashish; Thompson, Maethonia; Chen, Zhihong; Cleary, Thomas P.; Lee, Thomas B. K. Organic Process Research and Development, 2001 , vol. 5, # 6 p. 604 - 608

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Citation Number: 59

Abstract

A new method for N-methylation of indoles using environmentally safe and less toxic methylating reagent, dimethyl carbonate (DMC), has been developed. The effect of various functional groups on the indole ring has been investigated. This method provides the ...