Synthesis

Efficient N-aroylation of substituted indoles with N-aroylbenzotriazoles

AR Katritzky, L Khelashvili, PP Mohapatra, PJ Steel

Index: Katritzky, Alan R.; Khelashvili, Levan; Mohapatra, Prabhu P.; Steel, Peter J. Synthesis, 2007 , # 23 p. 3673 - 3677

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Citation Number: 10

Abstract

Abstract Stable and easily accessible N-aroylbenzotriazoles react with indoles in the presence of a base to afford the corresponding N-aroylindoles in yields averaging 70%. This method is effective even when both coupling reagents possess electron-donating substituents.