Facile microwave-assisted michael addition of diphenacyl sulfides to chalcones under solvent-free conditions: Generation of symmetrical and unsymmetrical 1, 5- …

…, MJ Shanmugam, S Muthusubramanian

Index: Paul, Nidhin; Shanmugam, Muniyappapillai Jeganathan; Muthusubramanian, Shanmugam Synthetic Communications, 2013 , vol. 43, # 1 p. 129 - 138

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Citation Number: 7

Abstract

Michael addition of enolates to α,β-unsaturated carbonyl compound is an effective method for the synthesis of 1,5-dicarbonyl compounds through the formation of CC bond which can be further transformed to multifunctional molecules via Robinson annulation. [ 1 1. For examples of Michael addition of enolates, see (a) Tozawa , T. ; Yamane , Y. ; Mukaiyama , T. Enantioselective synthesis of 3,4-dihydropyran-2-ones by chiral quaternary ammonium phenoxide–catalyzed ...