1,3-Diphenyl-2-propen-1-one

Modify Date: 2024-01-06 20:02:40

1,3-Diphenyl-2-propen-1-one structure	Common Name	1,3-Diphenyl-2-propen-1-one
	CAS Number	94-41-7	Molecular Weight	208.25500
	Density	N/A	Boiling Point	208 °C25 mm Hg(lit.)
	Molecular Formula	C₁₅H₁₂O	Melting Point	55-59 °C
	MSDS	Chinese USA	Flash Point	>230 °F
	Symbol	GHS07	Signal Word	Warning

Use of 1,3-Diphenyl-2-propen-1-one

Chalcone is isolated from Glycyrrhizae inflata and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities[1].

Name	chalcone
Synonym	More Synonyms

Description	Chalcone is isolated from Glycyrrhizae inflata and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Chalcone derivatives are synthesized by Claisen-Shimidt base-catalyzed condensation of appropriate aromatic ketones or substituted aromatic ketones with benzaldehydes or substituted benzaldehydes[1].
References	[1]. Shailendra Mandge,et al. Synthesis and Characterization of Some Chalcone Derivatives. Trends in Applied Sciences Research Volume 2 (1): 52-56, 2007

Boiling Point	208 °C25 mm Hg(lit.)
Melting Point	55-59 °C
Molecular Formula	C₁₅H₁₂O
Molecular Weight	208.25500
Flash Point	>230 °F
Exact Mass	208.08900
PSA	17.07000
LogP	3.58270

1,3-Diphenyl-2-propen-1-one MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FL6900000

CHEMICAL NAME :: Chalcone

CAS REGISTRY NUMBER :: 94-41-7

LAST UPDATED :: 199706

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H12-O

MOLECULAR WEIGHT :: 208.27

WISWESSER LINE NOTATION :: RV1U1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 681 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Cells - not otherwise specified

DOSE/DURATION :: 250 units/L

REFERENCE :: ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 35,629,1964

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn,Xi
Risk Phrases	R22:Harmful if swallowed. R36/37:Irritating to eyes and respiratory system .
Safety Phrases	S22-S36/37/39-S45
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UD5576750
HS Code	2914399090

Precursor 9
CAS#:4663-33-6 trans-1,3-Diphe... CAS#:98-86-2 Acetophenone CAS#:100-51-6 Benzyl alcohol CAS#:100-52-7 Benzaldehyde
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CAS#:143-66-8 Sodium tetraphe...
DownStream 10
CAS#:111783-13-2 2-oxo-4-(2-phen... CAS#:10475-15-7 2H-1-Benzopyran... CAS#:10173-87-2 2,4-diphenyl-4H... CAS#:103-82-2 Phenylacetic acid
CAS#:65-85-0 benzoic acid CAS#:451-40-1 2-Phenylacetophenone CAS#:151449-93-3 2-methyl-5,7-di... CAS#:448-61-3 2,4,6-TRIPHENYL...
CAS#:1961-97-3 1H-Indene, 3-phenyl- CAS#:4505-48-0 2-Phenylindene

HS Code	2914399090
Summary	2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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Comparative analysis of the main bioactive components of San-ao decoction and its series of formulations.

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A high performance liquid chromatographic (HPLC) method with diode array detection (DAD) was established for simultaneous determination of seven main bioactive components in San-ao decoction and its s...

Development of a stability-indicating LC method for determination of a synthetic chalcone derivative in a nanoemulsion dosage form and identification of the main photodegradation product by LC-MS.

J. Pharm. Biomed. Anal. 70 , 652-6, (2012)

This study aimed to develop and validate a stability indicating LC for the determination of 5-(2-benzoylethenyl)-N-benzyl-2 methoxybenzenesulfonamide (SCD - a synthetic chalcone derivative), and evalu...

EINECS 202-330-2

BENZALACETOPHENONE

benzylidene acetophenone

CHALKONE

MFCD00003082

Cinnamophenone

CHALCONE

PhCOCH=CHPh

styrylphenylketone

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1,3-Diphenyl-2-propen-1-one
Price: ￥198.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

Henan Tianfu Chemical Co., Ltd.
China
Product Name: CHALCONE 94-41-7
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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