Synthesis

An efficient method for the α-acetoxylation of ketones

J Sheng, X Li, M Tang, B Gao, G Huang

Index: Sheng, Jinmei; Li, Xiaolong; Tang, Mingfang; Gao, Botao; Huang, Guosheng Synthesis, 2007 , # 8 p. 1165 - 1168

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Citation Number: 46

Abstract

Abstract α-Acetoxylation of ketones catalyzed by iodobenzene using 30% aqueous hydrogen peroxide and acetic anhydride as the oxidant is an effective and economical method for the preparation of α-acetoxy ketones. The reaction gave the products in good yields without the addition of acetic acid and water.

~73%

~70%

~80%

~48%

~32%

~77%

~71%

~45%

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