Tetrahedron

Facile organocatalytic domino oxidation of diols to lactones by in situ-generated TetMe-IBX

S Jhulki, S Seth, M Mondal, JN Moorthy

Index: Jhulki, Samik; Seth, Saona; Mondal, Manas; Moorthy, Jarugu Narasimha Tetrahedron, 2014 , vol. 70, # 13 p. 2286 - 2293

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Citation Number: 5

Abstract

Abstract The domino oxidation of diols to lactones is an important transformation, and catalytic protocols that allow this conversion smoothly are scarce. Capitalizing on the established reactivity of tetramethyl-IBX (TetMe-IBX) and its in situ generation in the presence of a co-oxidant, such as oxone, we have shown that a variety of diols can be converted to the corresponding lactones in respectable yields by employing the precursor ...