e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Russian Chemical Bulletin

Condensation of 2-hydroxyacetophenones with trichloroacetonitrile as a route to 2-trichloromethylchromones and 4-hydroxycoumarins

VY Sosnovskikh, VA Kutsenko…

Index: Sosnovskikh; Kutsenko; Ovsyannikov Russian Chemical Bulletin, 2000 , vol. 49, # 3 p. 478 - 481

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Citation Number: 9

Abstract

Abstract Condensation of 2-hydroxyacetophenones with trichloroacetonitrile in the presence of N-methylanilinomagnesium bromide affords hydroxyaryl β-amino-β-trichloromethylvinyl ketones, which are converted into 2-trichloromethylchromones upon treatment with

7-methoxy-2-(trichloromethyl)-4H-chromen-4-one Structure

7-methoxy-2-(tr...

~52%

4-hydroxy-7-methoxycoumarin Structure

4-hydroxy-7-met...

2-trichloromethyl-4-chromone Structure

2-trichlorometh...

~63%

4-Hydroxycoumarin Structure

4-Hydroxycoumarin

6-methyl-2-(trichloromethyl)-4H-chromen-4-one Structure

6-methyl-2-(tri...

~69%

4-Hydroxy-6-methylcoumarin Structure

4-Hydroxy-6-met...

6-methoxy-2-(trichloromethyl)-4H-chromen-4-one Structure

6-methoxy-2-(tr...

~71%

2H-1-BENZOPYRAN-2-ONE, 4-HYDROXY-6-METHOXY Structure

2H-1-BENZOPYRAN...

ST 034307 Structure

~44%

6-chloro-4-hydroxycoumarin Structure

6-chloro-4-hydr...

Condensation of 2-hydroxyacetophenones with trichloroacetoni...

[Russian Chemical Bulletin, , vol. 49, # 3 p. 478 - 481]

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Pd-Catalyzed Allylic Alkylation Cascade with Dihydropyrans: ...

[Organic Letters, , vol. 15, # 10 p. 2430 - 2433]

Condensation of 2-hydroxyacetophenones with trichloroacetoni...

[Russian Chemical Bulletin, , vol. 49, # 3 p. 478 - 481]

Synthesis and biological evaluation of 4-(1, 2, 3-triazol-1-...

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