Carboxamides represent an important class of compounds found in numerous bioactive products,[1] such as top-sold medicines (ie, Lipitor, Lidoderm, Vyvanse),[2] as well as in biological and synthetic polymers (ie, proteins and nylons).[3] In addition, amides serve as versatile building blocks for the preparation of pharmaceuticals, agrochemicals, polymers, etc.[4] In general, substituted amides are prepared by substitution reactions of carboxylic ...
