Novel Anti??Markovnikov Regioselectivity in the Wacker Reaction of Styrenes

JA Wright, MJ Gaunt, JB Spencer

Index: Wright, Joseph A.; Gaunt, Matthew J.; Spencer, Jonathan B. Chemistry - A European Journal, 2006 , vol. 12, # 3 p. 949 - 955

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Citation Number: 49

Abstract

Abstract The Wacker reaction is one of the longest known palladium-catalysed organic transformations, and in the vast majority of cases proceeds with Markovnikov regioselectivity. Palladium (II)-mediated oxidation of styrenes was examined and in the absence of reoxidants was found to proceed in an anti-Markovnikov sense, giving aldehydes. Studies on the mechanism of this unusual transformation were carried out, and ...