Solid state nuclear bromination with N-bromosuccinimide. Part 1. Experimental and theoretical studies on some substituted aniline, phenol and nitro aromatic …

JARP Sarma, A Nagaraju

Index: Sarma, Jagarlapudi A.R.P.; Nagaraju, Akula Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 6 p. 1113 - 1118

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Citation Number: 34

Abstract

Solid state bromination of a number of substituted phenol, aniline and nitro aromatic compounds with N-bromosuccinimide yields exclusively the nuclear brominated products. Reactivity in the solid state depends on the reaction time, temperature and nature of the substituent on the substrate. The reaction apparently proceeds by an electrophilic aromatic substitution pathway. Molecular orbital and reaction free energy calculations also support such a ...