2,5-Dichloroaniline

Modify Date: 2026-07-03 09:57:47

2,5-Dichloroaniline structure	Common Name	2,5-Dichloroaniline
	CAS Number	95-82-9	Molecular Weight	162.017
	Density	1.4±0.1 g/cm3	Boiling Point	251.0±0.0 °C at 760 mmHg
	Molecular Formula	C₆H₅Cl₂N	Melting Point	48 °C
	MSDS	Chinese USA	Flash Point	100.4±21.8 °C
	Symbol	GHS06, GHS08, GHS09	Signal Word	Danger

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	2,5-dichloroaniline
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.4±0.1 g/cm3
Boiling Point	251.0±0.0 °C at 760 mmHg
Melting Point	48 °C
Molecular Formula	C₆H₅Cl₂N
Molecular Weight	162.017
Flash Point	100.4±21.8 °C
Exact Mass	160.979904
PSA	26.02000
LogP	2.71
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.614
InChIKey	AVYGCQXNNJPXSS-UHFFFAOYSA-N
SMILES	Nc1cc(Cl)ccc1Cl
Water Solubility	ca. 0.56 g/L (20 ºC)

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

2,5-Dichloroaniline MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX2610000

CHEMICAL NAME :: Aniline, 2,5-dichloro-

CAS REGISTRY NUMBER :: 95-82-9

BEILSTEIN REFERENCE NO. :: 1447438

LAST UPDATED :: 199710

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C6-H5-Cl2-N

MOLECULAR WEIGHT :: 162.02

WISWESSER LINE NOTATION :: ZR BG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00202

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3750 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3750 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 27300 mg/kg/13W-I

TOXIC EFFECTS :: Endocrine - changes in spleen weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4027 No. of Facilities: 116 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 2820 (estimated) No. of Female Employees: 246 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H301 + H311 + H331-H373-H410
Precautionary Statements	P261-P273-P280-P301 + P310-P311-P501
Hazard Codes	T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases	R23/24/25;R33;R50/53
Safety Phrases	S28-S36/37-S45-S60-S61-S28A
RIDADR	UN 3442 6.1/PG 2
WGK Germany	3
RTECS	BX2610000
Packaging Group	II
Hazard Class	6.1
HS Code	2921420090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:89-61-2 1,4-Dichloro-2-... CAS#:135145-90-3 (2,5-Dichloroph... CAS#:108-42-9 3-Chloroaniline CAS#:95-51-2 2-Chloroaniline
CAS#:305-15-7 2,5-dichlorophe... CAS#:6626-75-1 N-(2,5-Dichloro... CAS#:106-46-7 1,4-Dichlorobenzene CAS#:110-86-1 Pyridine
CAS#:588-07-8 Acetamide,N-(3-... CAS#:29551-86-8 N-chloro-m-chlo...
DownStream 10
CAS#:10586-68-2 4-[(4-amino-2,5... CAS#:110605-03-3 N-(2,5-dichloro... CAS#:4949-85-3 1-(2,5-Dichloro... CAS#:37680-65-2 2,2',5-PCB
CAS#:348-59-4 1,4-Dichloro-2-... CAS#:38380-02-8 2,2',3,4,5'-Pen... CAS#:3507-41-3 Benzothiazole, ... CAS#:4524-78-1 6-Bromo-2,4,5-t...
CAS#:608-27-5 2,3-Dichloroaniline CAS#:35693-99-3 2,2',5,5'-PCB

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2921420090
Summary	HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Synthesis, characterization and electrical properties of poly (2, 5-, 2, 3-and 3, 5-dichloroaniline) s. Part II. Copolymers with aniline. Diaz FR, et al.

Synthetic Metals 118(1-3) , 25-31, (2001)

Tautomeric properties and crystal structure of N−[2−hydroxy−1−naphthylidene] 2,5−dichloroaniline. Yildiz M, et al.

Cryst. Res. Technol. 41(6) , 600-606, (2006)

Determination of aromatic amines by solid-phase microextraction and gas chromatography−mass spectrometry in water samples. Muller L, et al.

J. Chromatogr. A. 791(1) , 221-230, (1997)

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01

Name: Adrenergic beta2 receptor (ADRB2) small molecule agonists, cell-based qHTS assay
Source: 824
External Id: ADRB2293

Total 215, Current Page 1 of 22

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

2,5-DICHLORO-BENZENAMINE

2,5-dichloro

Azobase DCA

2,5-dichlorophenylamine

scarletbasengg

2,5-DICHLOROANILINE D

1-amino-2,5-dichlorobenzene

2,5-DI CHLORO ANILINE

fastredsggbase

EINECS 202-455-2

2,5-Dichloroaniline

2,5-DICHLORANILIN

scarletbasegg

MFCD00007667

2,5-dichloro-aniline

1,4-Dichloro-2-aminobenzene

2,5-DICHLOROANILINE FOR SYNTHESIS

SearletbaseGGS

2,4-DICHLOROQUINOLINE

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of 2,5-dichloroaniline?

A: The English name of 2,5-dichloroaniline is 2,5-dichloroaniline.

Q: What is the polar surface area (PSA) of 2,5-dichloroaniline?

A: Polar surface area (PSA) of 2,5-dichloroaniline is 26.02000.

Q: How is the water solubility of 2,5-dichloroaniline?

A: Water solubility of 2,5-dichloroaniline: ca. 0.56 g/L (20 ºC).

Q: What is the InChIKey of 2,5-dichloroaniline?

A: InChIKey of 2,5-dichloroaniline is AVYGCQXNNJPXSS-UHFFFAOYSA-N.

Q: What is the molecular weight of 2,5-dichloroaniline?

A: Molecular weight of 2,5-dichloroaniline is 162.017.

Q: What is the boiling point of 2,5-dichloroaniline?

A: Boiling point of 2,5-dichloroaniline is 251.0±0.0 °C at 760 mmHg.

Q: What is the SMILES notation of 2,5-dichloroaniline?

A: SMILES notation of 2,5-dichloroaniline is Nc1cc(Cl)ccc1Cl.

Q: What English synonyms does 2,5-dichloroaniline have?

A: English synonyms of 2,5-dichloroaniline: 2,5-DICHLORO-BENZENAMINE, 2,5-dichloro, Azobase DCA, 2,5-dichlorophenylamine, scarletbasengg, 2,5-DICHLOROANILINE D, 1-amino-2,5-dichlorobenzene, 2,5-DI CHLORO ANILINE, fastredsggbase, EINECS 202-455-2, 2,5-Dichloroaniline, 2,5-DICHLORANILIN, scarletbasegg, MFCD00007667, 2,5-dichloro-aniline, 1,4-Dichloro-2-aminobenzene, 2,5-DICHLOROANILINE FOR SYNTHESIS, SearletbaseGGS, 2,4-DICHLOROQUINOLINE.

Q: What is the LogP of 2,5-dichloroaniline?

A: LogP of 2,5-dichloroaniline is 2.71.

Q: What is the safety information for 2,5-dichloroaniline?

A: Safety information for 2,5-dichloroaniline: S28-S36/37-S45-S60-S61-S28A.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2,5-Dichloroaniline
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,5-Dichloroaniline
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2,5-dichloroaniline
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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2,5-Dichloroaniline

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