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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Tetrahedron

Multi-functionalization of gallic acid towards improved synthesis of α-and β-DDB

A Alam, Y Takaguchi, H Ito, T Yoshida, S Tsuboi

Index: Tetrahedron, , vol. 61, # 7 p. 1909 - 1918

Full Text: HTML

Citation Number: 68

Abstract

... Tetrahedron. Volume 61, Issue 7, 14 February 2005, Pages 1909–1918. ... For the regioselective synthesis of bromo derivatives 11 and 14, 3-O-alkyl gallate 8 was prepared from 2 via the acetal 7. Methylenedioxy protection of 4,5-dihydroxy of 8 provided the fully protected methyl ...

 Related Synthetic Route
(4'-O-methyl)methyl gallate Structure

24093-81-0

(4'-O-methyl)me...

methyl iodide Structure

74-88-4

methyl iodide

~12%

Trimethylgallic acid methyl ester Structure

1916-07-0

Trimethylgallic...

Methyl 3-hydroxy-4,5-dimethoxybenzoate Structure

83011-43-2

Methyl 3-hydrox...

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Methyl gallate Structure

99-24-1

Methyl gallate

methyl iodide Structure

74-88-4

methyl iodide

~62%

(4'-O-methyl)methyl gallate Structure

24093-81-0

(4'-O-methyl)me...

Methyl 3-hydroxy-4,5-dimethoxybenzoate Structure

83011-43-2

Methyl 3-hydrox...

Learn More
Gallic acid Structure

149-91-7

Gallic acid

~%

Myristicin acid methyl ester Structure

22934-58-3

Myristicin acid...

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methyl 2-ethoxy-7-hydroxy-1,3-benzodioxole-5-carboxylate Structure

526221-05-6

methyl 2-ethoxy...

~%

Myristicin acid methyl ester Structure

22934-58-3

Myristicin acid...

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Diiodomethane Structure

75-11-6

Diiodomethane

methyl 2-bromo-3,4-dihydroxy-5-methoxybenzoate Structure

123685-25-6

methyl 2-bromo-...

~84%

Methyl 4-bromo-7-methoxybenzo[d][1,3]dioxole-5-carboxylate Structure

81474-46-6

Methyl 4-bromo-...

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Methyl gallate Structure

99-24-1

Methyl gallate

~%

Methyl 4-bromo-7-methoxybenzo[d][1,3]dioxole-5-carboxylate Structure

81474-46-6

Methyl 4-bromo-...

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Methyl 3,4-dihydroxy-5-methoxybenzoate Structure

3934-86-9

Methyl 3,4-dihy...

~%

Methyl 4-bromo-7-methoxybenzo[d][1,3]dioxole-5-carboxylate Structure

81474-46-6

Methyl 4-bromo-...

Learn More
Gallic acid Structure

149-91-7

Gallic acid

~%

Methyl 4-bromo-7-methoxybenzo[d][1,3]dioxole-5-carboxylate Structure

81474-46-6

Methyl 4-bromo-...

Learn More
methyl 2-ethoxy-7-hydroxy-1,3-benzodioxole-5-carboxylate Structure

526221-05-6

methyl 2-ethoxy...

~%

Methyl 4-bromo-7-methoxybenzo[d][1,3]dioxole-5-carboxylate Structure

81474-46-6

Methyl 4-bromo-...

Learn More
Methyl gallate Structure

99-24-1

Methyl gallate

methyl iodide Structure

74-88-4

methyl iodide

~12%

(4'-O-methyl)methyl gallate Structure

24093-81-0

(4'-O-methyl)me...

Methyl 3-hydroxy-4,5-dimethoxybenzoate Structure

83011-43-2

Methyl 3-hydrox...

Learn More
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Detail Synthetic Route


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