Heck reactions without salt formation: aromatic carboxylic anhydrides as arylating agents

MS Stephan, AJJM Teunissen…

Index: Stephan, Massoud S.; Teunissen, Antonius J. J. M.; Verzijl, Gerard K. M.; De Vries, Johannes G. Angewandte Chemie - International Edition, 1998 , vol. 37, # 5 p. 662 - 664

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Citation Number: 138

Abstract

Abstract Environmentally benign and economical production of arylated olefins can be achieved by a new variant of the Heck reaction in which no halogen salts are formed. The trick is the use of aromatic carboxylic anhydrides 1 as arylating agents. With halide-activated palladium chloride as catalyst, which requires no phosphane ligands, the olefins 2 can be prepared according to Equation (a) in good yields.