In general, 5-nitroimidazoles like metronidazole or ornidazole (Figure 1) are valuable drugs for treatment, of several protozoal diseases as well as for treating infections due to anaerobic bacteria [1]. The nitroimidazoles used therapeutically are 5-nitroimidazoles that have substituents at N-1 and C-2 but lack a substituent at C-4 [2], whereas the 4- nitroimidazoles have no significant therapeutic value [3-4]. Synthesis of biologically active ...