(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500

Modify Date: 2024-01-04 13:21:22

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 Structure
(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 structure
 Common Name (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500
CAS Number 171259-81-7 Molecular Weight 267.08
Density N/A Boiling Point N/A
Molecular Formula C7H11BrN2O4 Melting Point 205-208°C
MSDS N/A Flash Point N/A

 Use of (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500


(RS)-AMPA ((±)-AMPA) hydrobromide is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].

 Names

Name (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Hydrobromide
Synonym More Synonyms

  Biological Activity

Description (RS)-AMPA ((±)-AMPA) hydrobromide is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
Related Catalog
References

[1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62.  

[2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5.  

 Chemical & Physical Properties

Melting Point 205-208°C
Molecular Formula C7H11BrN2O4
Molecular Weight 267.08
Exact Mass 265.99000
PSA 109.58000
LogP 1.30140

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2934999090

 Synthetic Route

diethyl acetamido[(3-methoxy-5-methylisoxazol-4-yl)methyl]malonate structure

diethyl acetami...

CAS#:75989-23-0

~90%

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 Structure

(R,S)-α-Amino-3...

CAS#:171259-81-7

Literature: Hanson, Robert N.; Mohamed, Fand A. Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 345 - 348
3-methoxy-4-hydroxymethyl-5-methylisoxazole structure

3-methoxy-4-hyd...

CAS#:75989-21-8

~%

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 Structure

(R,S)-α-Amino-3...

CAS#:171259-81-7

Literature: Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833
Isoxazole, 4-(chloromethyl)-3-methoxy-5-methyl- (9CI) structure

Isoxazole, 4-(c...

CAS#:75989-22-9

~%

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 Structure

(R,S)-α-Amino-3...

CAS#:171259-81-7

Literature: Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833
4-Isoxazolecarboxylicacid,3-methoxy-5-methyl-(8CI,9CI) structure

4-Isoxazolecarb...

CAS#:16877-56-8

~%

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 Structure

(R,S)-α-Amino-3...

CAS#:171259-81-7

Literature: Hanson, Robert N.; Mohamed, Fand A. Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 345 - 348
3-Bromo-5-methylisoxazole-4-carboxylic acid structure

3-Bromo-5-methy...

CAS#:130742-22-2

~%

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 Structure

(R,S)-α-Amino-3...

CAS#:171259-81-7

Literature: Hanson, Robert N.; Mohamed, Fand A. Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 345 - 348
METHYL 3-BROMO-5-METHYLISOXAZOLE-4-CARBOXYLATE structure

METHYL 3-BROMO-...

CAS#:188686-98-8

~%

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 Structure

(R,S)-α-Amino-3...

CAS#:171259-81-7

Literature: Hanson, Robert N.; Mohamed, Fand A. Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 345 - 348
ethyl 3-methoxy-5-methylisoxazole-4-carboxylate structure

ethyl 3-methoxy...

CAS#:75989-20-7

~%

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 Structure

(R,S)-α-Amino-3...

CAS#:171259-81-7

Literature: Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-(3-Hydroxy-5-methyl-1,2-oxazol-4-yl)alanine hydrobromide (1:1)
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Chemsrc provides CAS#:171259-81-7 MSDS, density, melting point, boiling point, structure, etc. Its name is (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500>> amp version: (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500

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