Advanced Synthesis & Catalysis

Copper??Catalyzed Oxidative Transformation of Aryl Propargylic Azides to Aryl Propiolonitriles

T Wang, H Yin, N Jiao

Index: Wang, Teng; Yin, Hang; Jiao, Ning Advanced Synthesis and Catalysis, 2013 , vol. 355, # 6 p. 1207 - 1210

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Citation Number: 7

Abstract

Abstract A concise copper (I)-catalyzed oxidative transformation of aryl propargyl azides to aryl propiolonitriles has been developed. Aryl propiolonitrile derivatives can be obtained in moderate to good yields by this strategy. An oxidative Schmidt rearrangement is involved in this transformation.

~78%

~47%

~65%

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