Tetrahedron letters

Facile conversion of carboxamides to nitriles

K Mai, G Patil

Index: Mai, Khuong; Patil, Ghanshyam Tetrahedron Letters, 1986 , vol. 27, # 20 p. 2203 - 2206

Full Text: HTML

Citation Number: 34

Abstract

Abstract Alkyl, aralkyl, aryl, heteroaryl carboxamides bearing various functionalities are readily converted to the corresponding nitriles in good yields using the liquid “diphosgene”, trichloromethyl chloroformate, as dehydrating agent. In many cases, the procedure does not