e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

The Journal of Organic Chemistry

Chemoselective hydrolysis of amides in the presence of esters by copper (II)/glyoxal: metal complexation as the core motif for selective amide activation

L Singh, RN Ram

Index: Singh, Latika; Ram, Ram N. Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 710 - 711

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Citation Number: 14

Abstract

Summary: A general method for selective hydrolysis of amides in the presence of esters with Cu(II)/glyoxal in aqueous medium is reported. The hydrolyses of carboxamides and carboxylic esters are classical reactions of fundamental importance in chemistry and biology. Due to the

Benzamide,N-methyl-4-nitro- Structure

Benzamide,N-met...

~49%

4-Nitrobenzoic acid Structure

4-Nitrobenzoic acid

(E)-N-Methyl-3-phenylacrylamide Structure

(E)-N-Methyl-3-...

~89%

Cinnamic acid Structure

Benzamide,4-methoxy-N-methyl- Structure

Benzamide,4-met...

~87%

p-Anisic acid Structure

N-METHYL-P-TOLUAMIDE Structure

N-METHYL-P-TOLUAMIDE

~78%

4-Methylbenzoic acid Structure

4-Methylbenzoic acid

Benzenecarboximidic acid, N-methyl- (9CI) Structure

Benzenecarboxim...

~80%

benzoic acid Structure

N-ETHYLBENZAMIDE Structure

N-ETHYLBENZAMIDE

~70%

benzoic acid Structure

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Chemiluminescence of secondary peroxy esters

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