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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

A convenient chemical-microbial method for developing fluorinated pharmaceuticals

TV Bright, F Dalton, VL Elder, CD Murphy…

Index: Organic and Biomolecular Chemistry, , vol. 11, # 7 p. 1135 - 1142

Full Text: HTML

Citation Number: 27

Abstract

... O'Connor a and Graham Sandford * b a UCD School of Biomolecular and Biomedical ... offer an attractive alternative to conventional resource-intensive bio- and medicinal chemistry approaches. ... The solution was extracted using ethyl acetate and the organic layers combined and ...

 Related Synthetic Route
4-Phenyltoluene Structure

644-08-6

4-Phenyltoluene

~%

4-Biphenylylmethanol Structure

3597-91-9

4-Biphenylylmethanol

4-Biphenylcarboxylic acid Structure

92-92-2

4-Biphenylcarbo...

4-Phenyltoluene Structure

644-08-6

4-Phenyltoluene

~%

4'-Hydroxy-4-biphenylcarboxylic acid Structure

58574-03-1

4'-Hydroxy-4-bi...

4-FLUORO-4'-METHYL-1,1'-BIPHENYL Structure

72093-43-7

4-FLUORO-4'-MET...

~%

4'-Fluoro-4-biphenylcarboxylic acid Structure

5731-10-2

4'-Fluoro-4-bip...

4-Bromotoluene Structure

106-38-7

4-Bromotoluene

4-Fluorobenzeneboronic acid Structure

1765-93-1

4-Fluorobenzene...

~%

4'-Fluoro-4-biphenylcarboxylic acid Structure

5731-10-2

4'-Fluoro-4-bip...

4-Phenyltoluene Structure

644-08-6

4-Phenyltoluene

~%

4-Biphenylylmethanol Structure

3597-91-9

4-Biphenylylmethanol

4-Biphenylcarboxylic acid Structure

92-92-2

4-Biphenylcarbo...

Ethyl 4-bromobenzoate Structure

5798-75-4

Ethyl 4-bromobe...

2-Fluorophenylboronic acid Structure

1993-03-9

2-Fluorophenylb...

~%

2'-Fluoro-[1,1'-biphenyl]-4-carboxylic acid Structure

365-12-8

2'-Fluoro-[1,1'...

4-Fluorobenzeneboronic acid Structure

1765-93-1

4-Fluorobenzene...

~%

4'-Fluoro-4-biphenylol Structure

324-94-7

4'-Fluoro-4-bip...

4-Bromoanisole Structure

104-92-7

4-Bromoanisole

~%

4'-Fluoro-4-biphenylol Structure

324-94-7

4'-Fluoro-4-bip...

4-Fluorobenzeneboronic acid Structure

1765-93-1

4-Fluorobenzene...

~%

4'-Fluoro-4-biphenylol Structure

324-94-7

4'-Fluoro-4-bip...

4-(4-fluorophenyl)-4-hydroxy-1-cyclohexanone Structure

36716-69-5

4-(4-fluorophen...

4-Bromoanisole Structure

104-92-7

4-Bromoanisole

~%

4'-Fluoro-4-biphenylol Structure

324-94-7

4'-Fluoro-4-bip...

4-(4-fluorophenyl)-4-hydroxy-1-cyclohexanone Structure

36716-69-5

4-(4-fluorophen...

4-FLUORO-4'-METHOXYBIPHENYL Structure

450-39-5

4-FLUORO-4'-MET...

~%

4'-Fluoro-4-biphenylol Structure

324-94-7

4'-Fluoro-4-bip...

4-(4-fluorophenyl)-4-hydroxy-1-cyclohexanone Structure

36716-69-5

4-(4-fluorophen...

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Detail Synthetic Route


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