Journal of the American Chemical Society

2', 5'-DNA containing guanine and cytosine forms stable duplexes

KE Jung, C Switzer

Index: Jung Kyeong Eun; Switzer Journal of the American Chemical Society, 1994 , vol. 116, # 14 p. 6059 - 6061

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Citation Number: 40

Abstract

Abstract: 2', 5 '-linked DNA oligomers bearing the bases guanine and cytosine are found to associate. Three 2', 5'-DNA strands composed entirely of the bases guanine and cytosine, two mutually complementary dodecamers, and a selfcomplementary octamer were prepared. Melting temperatures and free energies of duplex formation were determined for these oligomers and their natural, 3', 5'-linked DNA counterparts. From these data it was ...

~65%

CONFORMATIONAL RIGIDITY INTRODUCED BY 2′, 5′-PHOSPHODIESTER ...

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