N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYCYTIDINE

Modify Date: 2024-04-03 13:51:02

N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYCYTIDINE Structure
N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYCYTIDINE structure
Common Name N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYCYTIDINE
CAS Number 86234-45-9 Molecular Weight 633.69
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C37H35N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-3'-DEOXYCYTIDINE


N4-Benzoyl-5’-O-(4,4-dimethoxytrityl)-3’-deoxy cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name N-[1-[(2R,3R,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
Synonym More Synonyms

  Biological Activity

Description N4-Benzoyl-5’-O-(4,4-dimethoxytrityl)-3’-deoxy cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C37H35N3O7
Molecular Weight 633.69
Exact Mass 633.247498
PSA 121.14000
LogP 6.22
Index of Refraction 1.626

 Synthetic Route

 Synonyms

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-deoxycytidine
N4-benzoyl-5'-O-dimethoxytrityl-3'-deoxycytidine
N4-Benzoyl-3A'A inverted exclamation markA'A-deoxy-5A'A inverted exclamation markA'A-O-DMT-D-cytidine
N4-benzoyl-5'-O-dimethoxytrityl-3'-deoxyribicytidine
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-
N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine
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