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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Journal of Heterocyclic Chemistry

Synthesis of 1, 2, 3??Triazole Substituted Isoxazoles via Copper (I) Catalyzed Cycloaddition

PV Ramana, AR Reddy

Index: Journal of Heterocyclic Chemistry, , vol. 49, # 3 p. 621 - 627

Full Text: HTML

Citation Number: 2

Abstract

... Journal of Heterocyclic Chemistry: Previous article in issue: Studies on Reactive Pyridylketones Formed by Weinreb Transformations ... These two protons underwent propargylic 4 J coupling and was split into doublet and triplet. ...

 Related Synthetic Route
Benzaldehyde Structure

100-52-7

Benzaldehyde

~%

4-ISOXAZOLECARBOXYLIC ACID, 5-METHYL-3-PHENYL-, METHYL ESTER Structure

2065-28-3

4-ISOXAZOLECARB...

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Benzaldoxime Structure

932-90-1

Benzaldoxime

~%

4-ISOXAZOLECARBOXYLIC ACID, 5-METHYL-3-PHENYL-, METHYL ESTER Structure

2065-28-3

4-ISOXAZOLECARB...

Learn More
2-chloro-6-fluorophenyl chlorooxime Structure

51088-25-6

2-chloro-6-fluo...

Methyl acetoacetate Structure

105-45-3

Methyl acetoacetate

~%

METHYL 3-(2-CHLORO-6-FLUOROPHENYL)-5-METHYLISOXAZOLE-4-CARBOXYLATE Structure

4415-09-2

METHYL 3-(2-CHL...

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2-CHLORO-6-FLUOROBENZALDOXIME Structure

443-33-4

2-CHLORO-6-FLUO...

~%

METHYL 3-(2-CHLORO-6-FLUOROPHENYL)-5-METHYLISOXAZOLE-4-CARBOXYLATE Structure

4415-09-2

METHYL 3-(2-CHL...

Learn More
2-Chloro-6-fluorobenzaldehyde Structure

387-45-1

2-Chloro-6-fluo...

~%

METHYL 3-(2-CHLORO-6-FLUOROPHENYL)-5-METHYLISOXAZOLE-4-CARBOXYLATE Structure

4415-09-2

METHYL 3-(2-CHL...

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2-Chlorobenzaldehyde Structure

89-98-5

2-Chlorobenzaldehyde

~%

3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid Structure

23598-72-3

3-(2-Chlorophen...

Learn More
3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid Structure

23598-72-3

3-(2-Chlorophen...

~94%

3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride Structure

25629-50-9

3-(2-chlorophen...

Learn More
2-Chlorobenzaldehyde Structure

89-98-5

2-Chlorobenzaldehyde

~%

3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride Structure

25629-50-9

3-(2-chlorophen...

Learn More
4-ISOXAZOLECARBOXYLIC ACID, 5-METHYL-3-PHENYL-, METHYL ESTER Structure

2065-28-3

4-ISOXAZOLECARB...

~%

5-Methyl-3-phenylisoxazole-4-carbonyl chloride Structure

16883-16-2

5-Methyl-3-phen...

Learn More
Benzaldehyde Structure

100-52-7

Benzaldehyde

~%

5-Methyl-3-phenylisoxazole-4-carbonyl chloride Structure

16883-16-2

5-Methyl-3-phen...

Learn More
Alpha-Chlorobenzaldoxime Structure

698-16-8

Alpha-Chloroben...

~%

5-Methyl-3-phenylisoxazole-4-carbonyl chloride Structure

16883-16-2

5-Methyl-3-phen...

Learn More
Benzaldoxime Structure

932-90-1

Benzaldoxime

~%

5-Methyl-3-phenylisoxazole-4-carbonyl chloride Structure

16883-16-2

5-Methyl-3-phen...

Learn More
Related Articles: More...
Reduction of cyclic compounds having nitrogen-oxygen linkage...

[Kijima, Masashi; Nambu, Yoko; Endo, Takeshi Journal of Organic Chemistry, 1985 , vol. 50, # 7 p. 1140 - 1142]
Efficient regioselective synthesis of 4??and 5??substituted ...

[Lasri, Jamal; Mukhopadhyay, Suman; Charmier, M. Adilia Januario Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1385 - 1389]
Highly Substituted Isoxazoles: The Baylis-Hillman reaction o...

[Synthesis, , # 9 p. 1347 - 1356]

Detail Synthetic Route


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