Tetrahedron Letters

Palladium (0) nanoparticle-catalyzed sp 2 C–H activation: a convenient route to alkyl–aryl ketones by direct acylation of aryl bromides and iodides with aldehydes

L Adak, S Bhadra, BC Ranu

Index: Adak, Laksmikanta; Bhadra, Sukalyan; Ranu, Brindaban C. Tetrahedron Letters, 2010 , vol. 51, # 29 p. 3811 - 3814

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Citation Number: 27

Abstract

Palladium (0) nanoparticles efficiently catalyze aliphatic aldehyde C–H functionalization by aryl halides to produce alkyl–aryl ketones in good yields. A wide range of substituted aryl and hetero-aryl bromides/iodides and open-chain aldehydes of varied chain length participated in this reaction.

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