Tetrahedron

Synthesis of heterocycles via enamines—X: Reactions of 1-substituted-4, 4, 6-trimethyl-1, 4-dihydropyrimidine-2 (3h) thione derivatives with α-halogenated carboxylic …

H Singh, P Singh, K Deep

Index: Singh, Harjit; Singh, Paramjit; Deep, Kanwal Tetrahedron, 1983 , vol. 39, # 9 p. 1655 - 1660

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Citation Number: 7

Abstract

2, 4-Dioxathiazolidine derivatives (7) have been obtained in synthetically useful yields by the condensations of easily available 1-substituted-4, 4, 6-trimethyl-1, 4-dihydropyrimidine-2 (3H) thione derivatives (4) and α-halogenated carboxylic acids in aqueous medium. The condensations of 4 with α-haloketones in ethanol containing cone HCl furnish 2-oxa-4- thiazolines (8). The condensations of N, N-dialkyl-N'-aryl thioureas or aryl thiourethanes ...