Efficient cross-coupling of aryl Grignard reagents with alkyl halides by recyclable ionic iron (III) complexes bearing a bis (phenol)-functionalized benzimidazolium …

…, CF Xie, YF Wu, HM Sun, Q Shen, Y Zhang

Index: Xia, Chong-Liang; Xie, Cun-Fei; Wu, Yu-Feng; Sun, Hong-Mei; Shen, Qi; Zhang, Yong Organic and Biomolecular Chemistry, 2013 , vol. 11, # 46 p. 8135 - 8144

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Citation Number: 11

Abstract

Following the original work of Kochi et al., 2a recent reports on the alkylation of aryl Grignard reagents using unactivated primary or secondary alkyl halides show the potential of iron-based catalysts, whereas palladium- or nickel-based catalysts do not perform as well because of competing β-hydride elimination reactions. 2b–e To date, a variety of iron-based catalysts have been designed and proven active for such cross-coupling. For example, while simple iron salts such as ...