The Journal of Organic Chemistry

Preparation of 2-fluoropyridines via base-induced decomposition of N-fluoropyridinium salts

T Umemoto, G Tomizawa

Index: Umemoto, Teruo; Tomizawa, Ginjiro Journal of Organic Chemistry, 1989 , vol. 54, # 7 p. 1726 - 1731

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Citation Number: 74

Abstract

N-Fluoropyridinium salts with either BF4-, SbF6-, or PF6-as a counteranion were treated with excess base such as triethylamine at room temperature to give 2-fluoropyridine in good yield. This method was successfully applied to the preparation of 2-fluoropyridine derivatives possessing electron-donating or-withdrawing substituents using substituted N- fluoropyridinium tetrafluoroborates. Pyridine-F2 compounds produced through reactions ...