2-Fluoro-4-methylpyridine
2-Fluoro-4-methylpyridine structure
|
Common Name | 2-Fluoro-4-methylpyridine | ||
|---|---|---|---|---|
| CAS Number | 461-87-0 | Molecular Weight | 111.117 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 161.4±20.0 °C at 760 mmHg | |
| Molecular Formula | C6H6FN | Melting Point | 160-161 °C (lit.) | |
| MSDS | Chinese USA | Flash Point | 51.4±21.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-Fluoro-4-methylpyridine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 161.4±20.0 °C at 760 mmHg |
| Melting Point | 160-161 °C (lit.) |
| Molecular Formula | C6H6FN |
| Molecular Weight | 111.117 |
| Flash Point | 51.4±21.8 °C |
| Exact Mass | 111.048424 |
| PSA | 12.89000 |
| LogP | 1.30 |
| Vapour Pressure | 3.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.477 |
| InChIKey | ZBFAXMKJADVOGH-UHFFFAOYSA-N |
| SMILES | Cc1ccnc(F)c1 |
| Storage condition | Room temperature. |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | 1993 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 3 |
| HS Code | 2933399090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
|
~30%
2-Fluoro-4-meth... CAS#:461-87-0 |
| Literature: Puy, Michael Van Der Tetrahedron Letters, 1987 , vol. 28, # 3 p. 255 - 258 |
|
~49%
2-Fluoro-4-meth... CAS#:461-87-0 |
| Literature: Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458 |
|
~64%
2-Fluoro-4-meth... CAS#:461-87-0 |
| Literature: Shestopalov, Anatoliy M.; Fedorov, Alexander E.; Rodinovskaya, Liudmila A.; Shestopalov, Alexander A.; Gakh, Andrei A. Tetrahedron Letters, 2009 , vol. 50, # 37 p. 5257 - 5259 |
|
~22%
2-Fluoro-4-meth... CAS#:461-87-0
Learn More
|
| Literature: Kiselyov; Strekowski Synthetic Communications, 1994 , vol. 24, # 16 p. 2387 - 2392 |
|
~21%
2-Fluoro-4-meth... CAS#:461-87-0
Learn More
|
| Literature: Kiselyov; Strekowski Synthetic Communications, 1994 , vol. 24, # 16 p. 2387 - 2392 |
|
~82%
2-Fluoro-4-meth... CAS#:461-87-0 |
| Literature: Umemoto, Teruo; Tomizawa, Ginjiro Journal of Organic Chemistry, 1989 , vol. 54, # 7 p. 1726 - 1731 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
|---|---|
| DownStream 10 | |
CAS#:3475-21-6
CAS#:455-69-6
CAS#:402-65-3
CAS#:4931-00-4
CAS#:260981-46-2
CAS#:302839-09-4
CAS#:303162-49-4
CAS#:1000188-57-7
CAS#:155705-46-7This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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The synthesis of 2-fluoro-4-and 2-fluoro-6-pyridinecarboxylic acid and derivatives. Roe A, et al.
J. Am. Chem. Soc. 71(12) , 4152-4153, (1949)
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The13C NMR, UV and IR spectra of 2-fluoropyridine methyl derivatives. Puszko A and Ciurla H.
Chem. Heterocycl. Comp. 35(6) , 677-687, (1999)
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2-Fluoro-4-pyridinylmethyl analogues of linopirdine as orally active acetylcholine release-enhancing agents with good efficacy and duration of action. Earl RA, et al.
J. Med. Chem. 41(23) , 4615-4622, (1998)
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-methyl-2-fluoropyridine |
| 2-Fluor-4-methyl-pyridin |
| 2-fluoro-4-methyl-pyridine |
| 2-Fluoro-4-picoline |
| 2-FLUORO-4-PICOLINE 2-FLUORO-4-METHYLPYRIDINE |
| 2-Fluoro-4-mehtylpyridine |
| T6NJ BF D1 |
| 2-fluoro-4-methlpyridine |
| 2-Fluoro-4-methylpyridine |
| MFCD00041224 |
| 2-fluoropicoline |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of 2-Fluoro-4-methylpyridine? |
| A: Molecular weight of 2-Fluoro-4-methylpyridine is 111.117. |
| Q: What is the boiling point of 2-Fluoro-4-methylpyridine? |
| A: Boiling point of 2-Fluoro-4-methylpyridine is 161.4±20.0 °C at 760 mmHg. |
| Q: What are the storage conditions for 2-Fluoro-4-methylpyridine? |
| A: Storage conditions for 2-Fluoro-4-methylpyridine: Room temperature. |
| Q: What English synonyms does 2-Fluoro-4-methylpyridine have? |
| A: English synonyms of 2-Fluoro-4-methylpyridine: 4-methyl-2-fluoropyridine, 2-Fluor-4-methyl-pyridin, 2-fluoro-4-methyl-pyridine, 2-Fluoro-4-picoline, 2-FLUORO-4-PICOLINE 2-FLUORO-4-METHYLPYRIDINE, 2-Fluoro-4-mehtylpyridine, T6NJ BF D1, 2-fluoro-4-methlpyridine, 2-Fluoro-4-methylpyridine, MFCD00041224, 2-fluoropicoline. |
| Q: What is the CAS number of 2-Fluoro-4-methylpyridine? |
| A: CAS number of 2-Fluoro-4-methylpyridine is 461-87-0. |
| Q: What are the upstream materials of 2-Fluoro-4-methylpyridine? |
| A: Related upstream materials(CAS) of 2-Fluoro-4-methylpyridine: 108-89-4;695-34-1;4926-28-7;75-05-8;116241-53-3. |
| Q: What is the melting point of 2-Fluoro-4-methylpyridine? |
| A: Melting point of 2-Fluoro-4-methylpyridine is 160-161 °C (lit.). |
| Q: What is the LogP of 2-Fluoro-4-methylpyridine? |
| A: LogP of 2-Fluoro-4-methylpyridine is 1.30. |
| Q: What is the SMILES notation of 2-Fluoro-4-methylpyridine? |
| A: SMILES notation of 2-Fluoro-4-methylpyridine is Cc1ccnc(F)c1. |
| Q: What is the InChIKey of 2-Fluoro-4-methylpyridine? |
| A: InChIKey of 2-Fluoro-4-methylpyridine is ZBFAXMKJADVOGH-UHFFFAOYSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |