Journal of the Chinese Chemical Society

A Novel Method for the Synthesis of α, β??Unsaturated Amides Mediated by Samarium Diiodide

CL Zhu, XX Wang

Index: Zhu, Chun-Lan; Wang, Xia-Xia Journal of the Chinese Chemical Society, 2005 , vol. 52, # 5 p. 953 - 955

Full Text: HTML

Citation Number: 1

Abstract

Abstract Promoted by Samarium diiodide (SmI 2), α, β-unsaturated amides were formed from nitrogen anions (formed in situ by the reduction of nitro compounds) and α, β-unsaturated esters. This reaction contrasts with the conjugate addition between amines and α, β- unsaturated esters promoted by samarium triiodide (SmI 3) and provides an alternative attractive way to obtain α, β-unsaturated amides using SmI 2.