Ligandfree CuTC-catalyzed N-arylation of amides, anilines and 4-aminoantipyrine: synthesis of N-arylacrylamides, 4-amido-N-phenylbenzamides and 4-amino (N- …

…, HD Xia, Z Zhang, YX Da, XC Wang

Index: Quan, Zheng-Jun; Xia, Hai-Dong; Zhang, Zhang; Da, Yu-Xia; Wang, Xi-Cun Applied Organometallic Chemistry, 2014 , vol. 28, # 2 p. 81 - 85

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Citation Number: 8

Abstract

N-Arylamides and diarylamines are important synthetic building blocks that are prevalent in many bioactive compounds and medicinal agents, and have important roles in organic synthesis and biological and pharmaceutical research.[1] As a more efficient and facile method, the transition metal-catalyzed coupling reaction of aryl halides or pseudo halides and amides or anilines has been attractive for many years.[2] In particular, the palladium-[ ...