Synthesis of mono-and N, N-disubstituted thioureas and N-acylthioureas

AR Katritzky, N Kirichenko, BV Rogovoy, J Kister…

Index: Katritzky, Alan R.; Kirichenko, Nataliya; Rogovoy, Boris V.; Kister, Jeremy; Tao, Hui Synthesis, 2004 , # 11 p. 1799 - 1805

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Citation Number: 13

Abstract

Abstract 1-Benzotriazole-1-carbothioamide (2), prepared from 1-cyanobenzotriazole (1) and hydrogen sulfide, reacts with amines to give thioureas 3a-e. Reactions of (benzotriazol-1-yl) carboximidamides 4a-d, fj and acyl-5a-f, ik or arylaminocarbonyl-5g, h (benzotriazol-1-yl) carboximidamides with hydrogen sulfide give the corresponding thioureas 3a-d, fj, and N- acylthioureas 6a-f, ik or N-carbamoylthioureas 6g, h, respectively.