Vilsmeier-Haack synthesis of aromatic aldehydes using bis-(trichloromethyl) carbonate and dimethylformamide

WG Shan, XJ Shi, WK Su

Index: Shan; Shi; Su Organic Preparations and Procedures International, 2004 , vol. 36, # 4 p. 337 - 340

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Citation Number: 14

Abstract

WG Shan, XJ Shi and W. K. Su* ... College of Pharmaceutical Sciences, Zhejiang University of Technology Hangzhou, 310014, P. R. CHINA ... The classical Vilsmeier-Haack reaction is a type of Friedel-Crafts reaction involving electrophilic substitution of suitable carbon nucleophiles with halomethylene-iminium salts.' Several substituted aldehydes have been synthesized by the Vilsmeier-Haack rea~tion.~” The traditional reagents involve a combination of ...