e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Synthesis of 1, 2, 4??triazoles and 1, 2, 4??oxadiazoles

…, JJ Hlavka, P Bitha, SA Lang

Index: Lin, Yang-i; Hlavka, Joseph J.; Bitha, Panayoto; Lang, S. A. Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1693 - 1695

Full Text: HTML

Citation Number: 5

Abstract

1694 Y.-i Lin, JJ Hlavka, P. Bitha and SA Lang, Jr. Table II Substituted 1,2,4-Oxadiazoles Vol. 20 AA npound R R' Yield, % Mp, °C Formula 5a 3,5-CF3C6H4 c6hs 94 100-102 C15H,F3N20 5f />-CF3C6H4 p

Phenylhydrazine hydrochloride Structure

Phenylhydrazine...

N-(benzenecarbonothioyl)-4-(trifluoromethyl)benzamide Structure

N-(benzenecarbo...

~85%

1,3-diphenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazole Structure

1,3-diphenyl-5-...

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4-(Trifluoromethyl)benzoyl chloride Structure

4-(Trifluoromet...

~%

1,3-diphenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazole Structure

1,3-diphenyl-5-...

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Thiobenzamide Structure

~%

1,3-diphenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazole Structure

1,3-diphenyl-5-...

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N-thioacetyl-4-chlorobenzamide Structure

N-thioacetyl-4-...

~96%

5-(4-chlorophenyl)-3-methyl-1,2,4-oxadiazole Structure

5-(4-chlorophen...

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methyl-Hydrazine, hydrochloride Structure

methyl-Hydrazin...

N-methanethioyl-3,5-dimethoxybenzamide Structure

N-methanethioyl...

~79%

5-(3,5-dimethoxyphenyl)-1-methyl-1,2,4-triazole Structure

5-(3,5-dimethox...

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N-(benzenecarbonothioyl)-4-(trifluoromethyl)benzamide Structure

N-(benzenecarbo...

~94%

3-phenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole Structure

3-phenyl-5-[4-(...

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4-(Trifluoromethyl)benzoyl chloride Structure

4-(Trifluoromet...

~%

3-phenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole Structure

3-phenyl-5-[4-(...

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Thiobenzamide Structure

~%

3-phenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole Structure

3-phenyl-5-[4-(...

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N-(4-methoxybenzenecarbothioyl)-4-(trifluoromethyl)benzamide Structure

N-(4-methoxyben...

~91%

3-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole Structure

3-(4-methoxyphe...

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N-(4-chlorophenylcarbonothioyl)-4-(trifluoromethyl)benzamide Structure

N-(4-chlorophen...

~95%

3-(4-chlorophenyl)-5-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole Structure

3-(4-chlorophen...

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4-(Trifluoromethyl)benzoyl chloride Structure

4-(Trifluoromet...

Thiobenzamide Structure

~31%

N-(benzenecarbonothioyl)-4-(trifluoromethyl)benzamide Structure

N-(benzenecarbo...

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N-thioacetyl-4-chlorobenzamide Structure

N-thioacetyl-4-...

Phenylhydrazine hydrochloride Structure

Phenylhydrazine...

~80%

5-(4-chlorophenyl)-3-methyl-1-phenyl-1,2,4-triazole Structure

5-(4-chlorophen...

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N-thioacetyl-4-chlorobenzamide Structure

N-thioacetyl-4-...

(2,2,2-trifluoroethyl)hydrazine hydrochloride Structure

(2,2,2-trifluor...

~99%

5-(4-chlorophenyl)-3-methyl-1-(2,2,2-trifluoroethyl)-1,2,4-triazole Structure

5-(4-chlorophen...

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methyl-Hydrazine, hydrochloride Structure

methyl-Hydrazin...

N-(benzenecarbonothioyl)-4-(trifluoromethyl)benzamide Structure

N-(benzenecarbo...

~81%

1-methyl-3-phenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazole Structure

1-methyl-3-phen...

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Thiobenzamide Structure

~%

1-methyl-3-phenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazole Structure

1-methyl-3-phen...

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(4-Bromophenyl)hydrazine hydrochloride Structure

(4-Bromophenyl)...

N-methanethioyl-3,5-dimethoxybenzamide Structure

N-methanethioyl...

~87%

1-(4-bromophenyl)-5-(3,5-dimethoxyphenyl)-1,2,4-triazole Structure

1-(4-bromopheny...

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N-methanethioyl-3,5-dimethoxybenzamide Structure

N-methanethioyl...

~92%

5-(3,5-dimethoxyphenyl)-1,2,4-oxadiazole Structure

5-(3,5-dimethox...

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N-ethanethioyl-3,5-dimethoxybenzamide Structure

N-ethanethioyl-...

~93%

5-(3,5-dimethoxyphenyl)-3-methyl-1,2,4-oxadiazole Structure

5-(3,5-dimethox...

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