Chemistry Letters

An Oxidative Transformation of N'-Phenylhydrazide to t-Butyl Ester Using a Copper (II) Halide-Lithium t-Butoxide System.

J Yamaguchi, T Aoyagi, R Fujikura, T Suyama

Index: Yamaguchi, Jun-Ichi; Aoyagi, Takashi; Fujikura, Ryohei; Suyama, Takayuki Chemistry Letters, 2001 , # 5 p. 466 - 467

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Citation Number: 3

Abstract

Among alkyl esters, the t-butyl group is an important pro- tecting group of carboxylic acid. Although many methods for the preparation of the t-butyl ester are reported,3 development of new methodology is still required. Concerning treatment of hydrazide 2 with some oxidants, the first investigation was reported by Curtius who oxidized 2 with iodine to the corresponding diacylhydrazines 6.4 Several oxidizing agents, such as chlorine,5 iodobenzene diacetate,6 NaIO4,7 ...