In vitro inhibitory activity of boropinic acid against Helicobacter pylori

…, L Menghini, R Pagiotti, P Angelini, S Genovese…

Index: Epifano, Francesco; Menghini, Luigi; Pagiotti, Rita; Angelini, Paola; Genovese, Salvatore; Curini, Massimo Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 21 p. 5523 - 5525

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Citation Number: 21

Abstract

In this study, we assessed in vitro minimum inhibitory concentration (MIC) values of some natural geranyloxycoumarins, geranyloxy-and isopentenyloxy acids against growth of Helicobacter pylori. Boropinic acid, active principle isolated from Boronia pinnata (Fam. Rutaceae), was seen to be the most effective compound with a MIC value of 1.62 μg/mL.