Synthetic communications

Suzuki Coupling of Cyclopropylboronic Acid With Aryl Halides Catalyzed by a Palladium–Tetraphosphine Complex

M Lemhadri, H Doucet, M Santelli

Index: Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice Synthetic Communications, 2006 , vol. 36, # 1 p. 121 - 128

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Citation Number: 26

Abstract

Abstract The tetraphosphine all??cis??1, 2, 3, 4??tetrakis (diphenylphosphinomethyl) cyclopentane (Tedicyp) in combination with [Pd (C3H5) Cl] 2 affords a very efficient catalyst for the coupling of cyclopropylboronic acid with aryl bromides and aryl chlorides. Higher reactions rates were observed with aryl bromides than with aryl chlorides; however, even in the presence of 1–0.4% of catalyst, a few aryl chlorides gave the coupling products in ...