[pGlu6, Pro9] SP6-11, a selective agonist for the substance P P-receptor subtype

…, C Gilon, M Chorev, Z Selinger

Index: Laufer, Ralph; Gilon, Chaim; Chorev, Michael; Selinger, Zvi Journal of Medicinal Chemistry, 1986 , vol. 29, # 7 p. 1284 - 1288

Full Text: HTML

Citation Number: 81

Abstract

Leu-Met-NHz) is an undecapeptide that acts as a neurotransmitter/modulator in the mammalian peripheral and central nervous systems.',* Substance P is part of a family of peptides known as tachykinins that share the common C-terminal sequence Phe-x-Gl~-Leu- Met-NH,.~ This family includes the peptides eledoisin, physalaemin, and kassinin, which are all of nonmammalian origin? Recently, two additional mammalian tachykinins were ...