Tetrahedron

Syntheses of polyfunctionalized resveratrol derivatives using Wittig and Heck protocols

M Chalal, D Vervandier-Fasseur, P Meunier, H Cattey…

Index: Chalal, Malik; Vervandier-Fasseur, Dominique; Meunier, Philippe; Cattey, Helene; Hierso, Jean-Cyrille Tetrahedron, 2012 , vol. 68, # 20 p. 3899 - 3907

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Citation Number: 17

Abstract

Improved protocols for Wittig reaction and palladium-catalyzed Heck coupling give expedient access to a series of unprecedented polyfunctionalized artificial-resveratrol derivatives. In the modified Wittig protocol, trimethylsilyl was used as a highly valuable protective group of the phenolic functions of starting aromatic materials. A clean O-alkylation of hydroxylated stilbenes with ethylene carbonate was also conducted. Thus, Wittig ...