Universal solid supports for the synthesis of oligonucleotides via a transesterification of H-phosphonate diester linkage

F Ferreira, A Meyer, JJ Vasseur…

Index: Wang, Weimin; Song, Quanlai; Jones, Roger A. Tetrahedron Letters, 1999 , vol. 40, # 51 p. 8971 - 8974

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Citation Number: 13

Abstract

... Volume: Page: ... Thus, LCAA-CPG was succinylated, and the hemiester was activated as an N-hydoxysuccinimide derivative that finally reacted with 6-amino-1-hexanol to give the desired solid support 1c (Scheme 6). A loading of 51 μmol/g was determined by ...