Amino Acid??Based Reoxidants for Aminohydroxylation: Application to the Construction of Amino Acid–Amino Alcohol Conjugates

…, A Flores, S Mesch, DL Poole, IA Roslan

Index: Donohoe, Timothy J.; Callens, Cedric K. A.; Flores, Aida; Mesch, Stefanie; Poole, Darren L.; Roslan, Ishmael A. Angewandte Chemie - International Edition, 2011 , vol. 50, # 46 p. 10957 - 10960

Full Text: HTML

Citation Number: 14

Abstract

In recent years, there has been a surge in reports of methodology aimed at synthesizing the 1, 2-amino alcohol motif.[1] Despite numerous studies, this key unit is still highly sought after because of its occurrence in many different organic compounds of value ranging from natural products to pharmaceutical agents.[2] Methods that allow for the regioselective and stereospecific addition of nitrogen and oxygen across a double bond are rare, and ...