Alternative Total Synthesis of (−)-Galanthamine Hydrobromide

…, A Bhattacharya, V Sundaram, R Banerjee…

Index: Reddy, Jambula Mukunda; Kumar, Kotagiri Vijay; Raju, Veeramalla; Bhaskar, Bolguddu Vijay; Himabindu, Vurumidi; Bhattacharya, Apurba; Sundaram, Venkatram; Banerjee, Rahul; Reddy, Ghanta Mahesh; Bandichhor, Rakeshwar Synthetic Communications, 2008 , vol. 38, # 13 p. 2138 - 2149

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Citation Number: 13

Abstract

An alternative total synthesis of (−)-galanthamine (1) hydrobromide, employing ecofriendly amidation, oxidative coupling, and classical resolution strategies is accomplished. ... An alternative total synthesis of (−)-galanthamine (1) hydrobromide, employing ecofriendly amidation, oxidative coupling, and classical resolution strategies is accomplished. ... Galanthamine 1, active against the acetylcholinesterase enzyme that increases postsynaptic membrane susceptibility to ...