Tetrahedron

Highly chemoselective hydrogenation method using novel finely dispersed palladium catalyst on silk-fibroin: its preparation and activity

T Ikawa, H Sajiki, K Hirota

Index: Ikawa, Takashi; Sajiki, Hironao; Hirota, Kosaku Tetrahedron, 2005 , vol. 61, # 8 p. 2217 - 2231

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Citation Number: 74

Abstract

A palladium–fibroin complex (Pd/Fib) was prepared by soaking silk-fibroin in MeOH solution of Pd (OAc) 2 for 2 days (under Ar atmosphere)—4 days (under air). Pd (OAc) 2 was gradually absorbed by fibroin and the rapid reduction of fibroin conjugated Pd (OAc) 2 proceeded with MeOH as a reductant at room temperature to be the Pd (0) complex. Pd/Fib catalyzed chemoselective hydrogenation of acetylenes, olefins and azides in the ...