Neuroscience Letters 2013-05-24

Edaravone alleviates hypoxia-acidosis/reoxygenation-induced neuronal injury by activating ERK1/2

Guibin Wang, Jingjing Su, Lingjuan Li, Jie Feng, Lei Shi, Wei He, Yunhai Liu

Index: Neurosci. Lett. 543 , 72-7, (2013)

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Abstract

• Hypoxia-acidosis/reoxygenation (H-A/R) exposure triggers neuronal injury. • Edaravone alleviates H-A/R-induced neuronal injury. • ERK1/2 activation is involved in the process of edaravone neuroprotection.