Chemical Communications 2013-03-21

Total synthesis of kottamide E.

Thomas B Parsons, Neil Spencer, Chi W Tsang, Richard S Grainger

Index: Chem. Commun. (Camb.) 49(23) , 2296-8, (2013)

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Abstract

The first synthesis of kottamide E, a marine natural product containing a 5,6-dibromoindole linked via a (Z)-enamide to an unusual 1,2-dithiolane-containing amino acid, is reported.