Anti-Cancer Agents in Medicinal Chemistry 2013-03-01

Quinones derived from plant secondary metabolites as anti-cancer agents.

Jin-Jian Lu, Jiao-Lin Bao, Guo-Sheng Wu, Wen-Shan Xu, Ming-Qing Huang, Xiu-Ping Chen, Yi-Tao Wang

Index: Anticancer Agents Med. Chem. 13(3) , 456-63, (2013)

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Abstract

Quinones are plant-derived secondary metabolites that present some anti-proliferation and anti-metastasis effects in various cancer types both in vitro and in vivo. This review focuses on the anti-cancer prospects of plant-derived quinones, namely, aloe-emodin, juglone, β-lapachol, plumbagin, shikonin, and thymoquinone. We intend to summarize their anti-cancer effects and investigate the mechanism of actions to promote the research and development of anti-cancer agents from quinones.

Related Compounds

Structure Name/CAS No. Articles
Shikonin Structure Shikonin
CAS:54952-43-1
Juglone Structure Juglone
CAS:481-39-0
Plumbagin Structure Plumbagin
CAS:481-42-5
Lapachol Structure Lapachol
CAS:84-79-7
Thymoquinone Structure Thymoquinone
CAS:490-91-5