An expeditious chemo-enzymatic route from glucose to catechol by the use of 2-deoxy-scyllo-inosose synthase

K Kakinuma, E Nango, F Kudo, Y Matsushima…

Index: Kakinuma, Katsumi; Nango, Eriko; Kudo, Fumitaka; Matsushima, Yoshitaka; Eguchi, Tadashi Tetrahedron Letters, 2000 , vol. 41, # 12 p. 1935 - 1938

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Citation Number: 27

Abstract

A potential two-step process to catechol from d-glucose comprising one-pot incubation of d- glucose with recombinant 2-deoxy-scyllo-inosose synthase (BtrC) and hexokinase, together with chemical reductive dehydration of the resulting 2-deoxy-scyllo-inosose with HI, was developed.