Chemical and Pharmaceutical Bulletin

Synthesis of various kinds of isoflavones, isoflavanes, and biphenyl-ketones and their 1, 1-diphenyl-2-picrylhydrazyl radical-scavenging activities

H Goto, Y Terao, S Akai

Index: Goto, Hideyuki; Terao, Yoshiyasu; Akai, Shuji Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 4 p. 346 - 360

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Citation Number: 41

Abstract

Forty-eight kinds of isoflavones (8), thirty-one isoflavanes (9), and forty-seven biphenyl- ketones (10, 10′) were synthesized from eleven kinds of substituted phenols (11) and six phenylacetic acids (12). Among them, seventy-five compounds are new. The radical scavenging activities of these compounds were evaluated using 1, 1-diphenyl-2- picrylhydrazyl (DPPH) at pH 6.0. We found that thirty-nine out of forty-three compounds ...