Cleavage of NH 2 terminal tyrosyl–peptide bonds using hypervalent iodine

RM Moriarty, M Sultana, YY Ku

Index: Moriarty, Robert M.; Sultana, Mumtaz; Ku, Yi-Yin Journal of the Chemical Society, Chemical Communications, 1985 , # 14 p. 974 - 975

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Abstract

Cleavage of NH2 Terminal Tyrosyl-Peptide Bonds using Hypervalent Iodine ... Robert M. Moriarty, Mumtaz Sultana, and Yi-Yin Ku Department of Chemistry, University of Illinois at Chicago, Box 4348, Chicago, Illinois 60680, USA ... The cleavage of NH2-tyrosine dipeptides with C6H51(OAc)2-MeOH-KOH yields 4-(methoxymethyl)phenol. ... We report a specific cleavage reaction of NH2-terminal tyrosyl peptides as expressed in Scheme 1 and summarised in ...