Synlett

Rhodium (I)-Catalyzed 1, 4-Addition of Arylboronic Acids to Acrylic Acid in Water: One-Step Preparation of 3-Arylpropionic Acids

NR Vautravers, B Breit

Index: Vautravers, Nicolas R.; Breit, Bernhard Synlett, 2011 , # 17 p. 2517 - 2520

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Citation Number: 5

Abstract

Abstract A practical method for the one-step preparation of 3-arylpropionic acids through rhodium-catalyzed 1, 4-addition of arylboronic acids to acrylic acid is reported. The method is applicable to a broad scope of aryl boronic acids and displays a wide functional group tolerance operating in water as the optimal reaction medium.