Journal of Organic Chemistry 2007-01-19

Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.

Fabrice Denes, Alejandro Perez-Luna, Fabrice Chemla

Index: J. Org. Chem. 72 , 398, (2007)

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Abstract

Enantioenriched 3,4-disubstituted beta-prolines have been prepared with a high diastereocontrol through a carbometalation reaction or through a domino Michael addition/carbometalation reaction.

Structure	Name/CAS No.	Molecular Formula	Articles
	Methyl 2-(bromomethyl)acrylate CAS:4224-69-5	C₅H₇BrO₂
	(S)-pyrrolidine-3-carboxylic acid CAS:72580-53-1	C₅H₉NO₂
	(R)-pyrrolidine-3-carboxylic acid CAS:72580-54-2	C₅H₉NO₂

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Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.

Abstract

Related Compounds