(S)-pyrrolidine-3-carboxylic acid

Modify Date: 2025-08-20 20:24:18

(S)-pyrrolidine-3-carboxylic acid structure	Common Name	(S)-pyrrolidine-3-carboxylic acid
	CAS Number	72580-53-1	Molecular Weight	115.131
	Density	1.186	Boiling Point	252 ºC
	Molecular Formula	C₅H₉NO₂	Melting Point	185-191°C
	MSDS	USA	Flash Point	106 ºC

Name	(3S)-pyrrolidine-3-carboxylic acid
Synonym	More Synonyms

Density	1.186
Boiling Point	252 ºC
Melting Point	185-191°C
Molecular Formula	C₅H₉NO₂
Molecular Weight	115.131
Flash Point	106 ºC
Exact Mass	115.063332
PSA	49.33000
LogP	-0.47
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.487

(S)-pyrrolidine-3-carboxylic acid MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.

J. Org. Chem. 72 , 398, (2007)

Enantioenriched 3,4-disubstituted beta-prolines have been prepared with a high diastereocontrol through a carbometalation reaction or through a domino Michael addition/carbometalation reaction.

Beta-proline analogues as agonists at the strychnine-sensitive glycine receptor.

J. Med. Chem. 35 , 233, (1992)

3-Carboxy-3,4-dehydropyrrolidine was found to bind with affinity equal to that of glycine in a [3H]strychnine binding assay. Simple substitution of the 1-, 2-, 4-, or 5-position resulted in marked los...

Endomorphin-1 analogues containing beta-proline are mu-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance.

J. Med. Chem. 45(12) , 2571-8, (2002)

In this paper we describe the synthesis and affinity toward the mu-opioid receptor of some tetrapeptides obtained from endomorphin-1, H-Tyr-Pro-Trp-Phe-NH(2) (1), by substituting each amino acid in tu...

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